I think the best way to get this rolling would be to speak to the owners of either the new anime store in the Lloyd center in Portland, or the new anime store, Silver Otaku, in Vancouver, and see if you can get some good advice, and possibly even support. Melch is right - you're going to need a TON of money to make this work, but if you can't get your cafe off the ground independently, perhaps you could even get one of the shops' owners to make this an annex or a part of one of the existing stores.
Also, alongside food, you should probably have a small manga/anime library and some couches where people can hang out and read/watch. There are lots of otaku in Northern Oregon, but we're really scattered, and if we had a place to hang out and relax year round, I think you might be able to capitalize enough to succeed monetarily. Maybe sell figures and such, too.