Well, on Naruto 3, a lot of characters have very high damaging comboes.
Gaara, Temari, Sandaime, Naruto, Sasuke, Kakashi, Kiba, Jiraiya, Rock,
Neji, Tenten, Haku, Gai, Orochimaru, and Mizuki have over half life comboes.
Temari, Naruto, Sasuke, Kakashi, Kiba, Neji, Jiraiya, and Gai all have about 3/4 life comboes that, if you have next to no Chakra, you can't escape them.
But, I haven't played the new game yet, so some of the comboes might be different, or the damage nerfed:(