There was a fighting game from the Ninja Turtles franchise; I think it was called "Ultimate Tournament." The basic storyline is that Shredder has entered some major televised tournament & the turtles decide to be involved, just to beat him. (Apparantly being amphibious ninjas means nothin in this game).
There were also some freaky other animal-creature-men in the game that, as far as I know, were only in the original comics. This one I know for sure, there was a female ninja, kinda like Mai Shiranui from Fatal Fury, who was never in the comics, never in the TV shows, & never in the movies. Her storyline is that she was in the tournament so as to win the prize money, so she could save her dojo.
I played the game once & got royally stomped on, (of course I was 10 or so). It was on the SNES, but I'm sure it was on other systems, too.