I use manga studio debut! I just started to use it seriously kind of recently though. For some reason, there don't seem to be a whole lot of tutorials or anything for it. Personally I'm kind of just experimenting to get what I like at this point. Haha, I guess my only tip would be to experiment then. Not very helpful. >.<;;
I kind of noticed that the help book that comes with it isn't the most helpful either. x.x